Long term effects of using medicinal marijuana

There is a documented withdrawal syndrome associated with the cessation of marijuana use after as little as a week. However this is not a common reaction and does not occur in the majority of users. The body does not become physically dependent. The symptoms of the withdrawal syndrome are; irritability, insomnia, mood swings, mild depression.

Long term marijuana use can cause some mood disturbances, depression, and apathy, even in otherwise healthy individuals. A "drug holiday" of at least 3 weeks every 3-4 months is a good idea. This can help the patient differentiate side effects of marijuana from the possible symptoms of an illness. The apathy associated with marijuana use can contribute or worsen other processes, such as generalized anxiety disorder, social isolation, and obesity.